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Q: My 10-week-old Chiweenie puppy was given a second set of puppy shots today in the hip area. About 3 hours later, swelling has developed to about the size of a grape, and he cries when touched. Is this normal?
A: Yes, this is common. The lump you are feeling is likely from the vaccine itself. This should easily resolve anywhere from 2 to 5 days from now.
For inflammation and comfort, you can try to put a warm compress on the area for 10 minutes every 6 hours.
It should resolve regardless. If after 6-8 weeks the lump is still there, then a biopsy or aspirate may be reasonable. This is more for precautionary reasons, as cancer or serious problems are very unlikely.
-- Answer from Critical Care Vet, a veterinarian on JustAnswer.
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